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Analytical parameters and validation of homopolymer detection in a pyrosequencing-based next generation sequencing system
BACKGROUND: Current technologies in next-generation sequencing are offering high throughput reads at low costs, but still suffer from various sequencing errors. Although pyro- and ion semiconductor sequencing both have the advantage of delivering long and high quality reads, problems might occur whe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822529/ https://www.ncbi.nlm.nih.gov/pubmed/29466940 http://dx.doi.org/10.1186/s12864-018-4544-x |