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Analytical parameters and validation of homopolymer detection in a pyrosequencing-based next generation sequencing system

BACKGROUND: Current technologies in next-generation sequencing are offering high throughput reads at low costs, but still suffer from various sequencing errors. Although pyro- and ion semiconductor sequencing both have the advantage of delivering long and high quality reads, problems might occur whe...

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Detalles Bibliográficos
Autores principales: Ivády, Gergely, Madar, László, Dzsudzsák, Erika, Koczok, Katalin, Kappelmayer, János, Krulisova, Veronika, Macek, Milan, Horváth, Attila, Balogh, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822529/
https://www.ncbi.nlm.nih.gov/pubmed/29466940
http://dx.doi.org/10.1186/s12864-018-4544-x

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