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The impact of metallothionein-II on microglial response to tumor necrosis factor-alpha (TNFα) and downstream effects on neuronal regeneration

BACKGROUND: The extracellular environment plays an important role in supporting the regeneration of axons after injury. Metallothionein-II (MTII) is a metal-binding protein known for its neuroprotective effect by directly stimulating the growth of axons after injury. Previous studies have shown that...

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Detalles Bibliográficos
Autores principales: Leung, Jacqueline Y. K., Bennett, William R., King, Anna E., Chung, Roger S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822550/
https://www.ncbi.nlm.nih.gov/pubmed/29471847
http://dx.doi.org/10.1186/s12974-018-1070-3