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A robust internal control for high-precision DNA methylation analyses by droplet digital PCR
BACKGROUND: Droplet digital PCR (ddPCR) allows absolute quantification of nucleic acids and has potential for improved non-invasive detection of DNA methylation. For increased precision of the methylation analysis, we aimed to develop a robust internal control for use in methylation-specific ddPCR....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822558/ https://www.ncbi.nlm.nih.gov/pubmed/29484034 http://dx.doi.org/10.1186/s13148-018-0456-5 |