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A robust internal control for high-precision DNA methylation analyses by droplet digital PCR

BACKGROUND: Droplet digital PCR (ddPCR) allows absolute quantification of nucleic acids and has potential for improved non-invasive detection of DNA methylation. For increased precision of the methylation analysis, we aimed to develop a robust internal control for use in methylation-specific ddPCR....

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Detalles Bibliográficos
Autores principales: Pharo, Heidi D., Andresen, Kim, Berg, Kaja C. G., Lothe, Ragnhild A., Jeanmougin, Marine, Lind, Guro E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822558/
https://www.ncbi.nlm.nih.gov/pubmed/29484034
http://dx.doi.org/10.1186/s13148-018-0456-5