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Neurodegenerative disease biomarkers Aβ(1–40), Aβ(1–42), tau, and p‐tau(181) in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral amyloid angiopathy

BACKGROUND: The Caribbean vervet monkey (Chlorocebus aethiops sabaeus) is a potentially valuable animal model of neurodegenerative disease. However, the trajectory of aging in vervets and its relationship to human disease is incompletely understood. METHODS: To characterize biomarkers associated wit...

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Detalles Bibliográficos
Autores principales: Chen, Jason A., Fears, Scott C., Jasinska, Anna J., Huang, Alden, Al‐Sharif, Noor B., Scheibel, Kevin E., Dyer, Thomas D., Fagan, Anne M., Blangero, John, Woods, Roger, Jorgensen, Matthew J., Kaplan, Jay R., Freimer, Nelson B., Coppola, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822592/
https://www.ncbi.nlm.nih.gov/pubmed/29484263
http://dx.doi.org/10.1002/brb3.903