Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo

BACKGROUND: Chondrogenic mesenchymal stem cells (MSCs) have not yet been used to address the clinical demands of large osteochondral joint surface defects. In this study, self-assembling tissue intermediates (TIs) derived from human periosteum-derived stem/progenitor cells (hPDCs) were generated and...

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Detalles Bibliográficos
Autores principales: Mendes, L. F., Katagiri, H., Tam, W. L., Chai, Y. C., Geris, L., Roberts, S. J., Luyten, F. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822604/
https://www.ncbi.nlm.nih.gov/pubmed/29467016
http://dx.doi.org/10.1186/s13287-018-0787-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822604/
https://www.ncbi.nlm.nih.gov/pubmed/29467016
http://dx.doi.org/10.1186/s13287-018-0787-3

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