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Extracellular α-synuclein levels are regulated by neuronal activity
BACKGROUND: α-Synuclein is a presynaptic protein abundant in the cytoplasmic compartment of neurons, whereas its presence in the extracellular space has also been observed under physiological conditions. Extracellular α-synuclein has pathological significance, exhibiting cellular toxicity and impair...
Autores principales: | Yamada, Kaoru, Iwatsubo, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822605/ https://www.ncbi.nlm.nih.gov/pubmed/29467003 http://dx.doi.org/10.1186/s13024-018-0241-0 |
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