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The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1

BACKGROUND: Our previous study has demonstrated that hepatocyte nuclear factor 1α (HNF1α) exerts potent therapeutic effects on hepatocellular carcinoma (HCC). However, the molecular mechanisms by which HNF1α reverses HCC malignancy need to be further elucidated. METHODS: lncRNA microarray was perfor...

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Detalles Bibliográficos
Autores principales: Ding, Chen-Hong, Yin, Chuan, Chen, Shi-Jie, Wen, Liang-Zhi, Ding, Kai, Lei, Shu-Juan, Liu, Jin-Pei, Wang, Jian, Chen, Kai-xian, Jiang, Hua-liang, Zhang, Xin, Luo, Cheng, Xie, Wei-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822613/
https://www.ncbi.nlm.nih.gov/pubmed/29466992
http://dx.doi.org/10.1186/s12943-018-0813-1