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A biomaterials approach to influence stem cell fate in injectable cell-based therapies

BACKGROUND: Numerous stem cell therapies use injection-based administration to deliver high-density cell preparations. However, cell retention rates as low as 1% have been observed within days of transplantation. This study investigated the effects of varying administration and formulation parameter...

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Detalles Bibliográficos
Autores principales: Amer, Mahetab H., Rose, Felicity R. A. J., Shakesheff, Kevin M., White, Lisa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822649/
https://www.ncbi.nlm.nih.gov/pubmed/29467014
http://dx.doi.org/10.1186/s13287-018-0789-1