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Palmitoylethanolamide Dampens Reactive Astrogliosis and Improves Neuronal Trophic Support in a Triple Transgenic Model of Alzheimer's Disease: In Vitro and In Vivo Evidence

Alzheimer's disease (AD) is a neurodegenerative disorder responsible for the majority of dementia cases in elderly people. It is widely accepted that the main hallmarks of AD are not only senile plaques and neurofibrillary tangles but also reactive astrogliosis, which often precedes detrimental...

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Detalles Bibliográficos
Autores principales: Bronzuoli, Maria Rosanna, Facchinetti, Roberta, Steardo, Luca, Romano, Adele, Stecca, Claudia, Passarella, Sergio, Cassano, Tommaso, Scuderi, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822864/
https://www.ncbi.nlm.nih.gov/pubmed/29576849
http://dx.doi.org/10.1155/2018/4720532