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Palmitoylethanolamide Dampens Reactive Astrogliosis and Improves Neuronal Trophic Support in a Triple Transgenic Model of Alzheimer's Disease: In Vitro and In Vivo Evidence
Alzheimer's disease (AD) is a neurodegenerative disorder responsible for the majority of dementia cases in elderly people. It is widely accepted that the main hallmarks of AD are not only senile plaques and neurofibrillary tangles but also reactive astrogliosis, which often precedes detrimental...
Autores principales: | Bronzuoli, Maria Rosanna, Facchinetti, Roberta, Steardo, Luca, Romano, Adele, Stecca, Claudia, Passarella, Sergio, Cassano, Tommaso, Scuderi, Caterina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822864/ https://www.ncbi.nlm.nih.gov/pubmed/29576849 http://dx.doi.org/10.1155/2018/4720532 |
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