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Evolution of HIV virulence in response to widespread scale up of antiretroviral therapy: a modeling study

There are global increases in the use of HIV antiretroviral therapy (ART), guided by clinical benefits of early ART initiation and the efficacy of treatment as prevention of transmission. Separately, it has been shown theoretically and empirically that HIV virulence can evolve over time; observed vi...

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Detalles Bibliográficos
Autores principales: Herbeck, Joshua T., Mittler, John E., Gottlieb, Geoffrey S., Goodreau, Steven M., Murphy, James T., Cori, Anne, Pickles, Michael, Fraser, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822883/
https://www.ncbi.nlm.nih.gov/pubmed/29492277
http://dx.doi.org/10.1093/ve/vew028