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ZP2495 Protects against Myocardial Ischemia/Reperfusion Injury in Diabetic Mice through Improvement of Cardiac Metabolism and Mitochondrial Function: The Possible Involvement of AMPK-FoxO3a Signal Pathway

Coronary heart disease patients with type 2 diabetes were subject to higher vulnerability for cardiac ischemia-reperfusion (I/R) injury. This study was designed to evaluate the impact of ZP2495 (a glucagon-GLP-1 dual-agonist) on cardiac function and energy metabolism after myocardial I/R injury in d...

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Detalles Bibliográficos
Autores principales: Li, Shuang, Wu, Hao, Han, Dong, Zhang, Mingming, Li, Na, Yu, Weihua, Sun, Dongdong, Sun, Zhongchan, Ma, Sai, Gao, Erhe, Li, Congye, Shen, Min, Cao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822888/
https://www.ncbi.nlm.nih.gov/pubmed/29576852
http://dx.doi.org/10.1155/2018/6451902