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Klotho ameliorates sepsis-induced acute kidney injury but is irrelevant to autophagy

BACKGROUND: The role of Klotho (KL) in sepsis-induced acute kidney injury (AKI) and the potential relationship between KL and autophagy in septic AKI were investigated. MATERIALS AND METHODS: A murine model of sepsis-induced AKI was established by cecal ligation and puncture (CLP). Mice undergoing C...

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Detalles Bibliográficos
Autores principales: Chen, Xinxin, Tong, Huan, Chen, Yu, Chen, Chaosheng, Ye, Jingjing, Mo, Qingfei, Zhao, Guangju, Hong, Guangliang, Zheng, Chenfei, Lu, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823070/
https://www.ncbi.nlm.nih.gov/pubmed/29497318
http://dx.doi.org/10.2147/OTT.S156891