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Klotho ameliorates sepsis-induced acute kidney injury but is irrelevant to autophagy
BACKGROUND: The role of Klotho (KL) in sepsis-induced acute kidney injury (AKI) and the potential relationship between KL and autophagy in septic AKI were investigated. MATERIALS AND METHODS: A murine model of sepsis-induced AKI was established by cecal ligation and puncture (CLP). Mice undergoing C...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823070/ https://www.ncbi.nlm.nih.gov/pubmed/29497318 http://dx.doi.org/10.2147/OTT.S156891 |