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Susceptibility to Aneuploidy in Young Mothers of Down Syndrome Children

We recently observed an increased frequency of binucleated micronucleated lymphocytes in women who had a Down syndrome (DS) child before 35 years of age and the fluorescence in situ hybridization analysis revealed that micronuclei were mainly originating from chromosomal malsegregation events, inclu...

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Detalles Bibliográficos
Autores principales: Migliore, Lucia, Migheli, Francesca, Coppedè, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823145/
https://www.ncbi.nlm.nih.gov/pubmed/19802501
http://dx.doi.org/10.1100/tsw.2009.122