ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity

High temperature requirement A1 (HtrA1) belongs to an ancient protein family that is linked to various human disorders. The precise role of exon 1-encoded N-terminal domains and how these influence the biological functions of human HtrA1 remain elusive. In this study, we traced the evolutionary orig...

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Detalles Bibliográficos
Autores principales: Gerhardt, Maximilian J, Marsh, Joseph A, Morrison, Margaux, Kazlauskas, Andrius, Khadka, Arogya, Rosenkranz, Stephan, DeAngelis, Margaret M, Saint-Geniez, Magali, Jacobo, Sarah Melissa P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823240/
https://www.ncbi.nlm.nih.gov/pubmed/28992183
http://dx.doi.org/10.1093/jmcb/mjx024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823240/
https://www.ncbi.nlm.nih.gov/pubmed/28992183
http://dx.doi.org/10.1093/jmcb/mjx024

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