Cargando…

Reproducibility of preclinical animal research improves with heterogeneity of study samples

Single-laboratory studies conducted under highly standardized conditions are the gold standard in preclinical animal research. Using simulations based on 440 preclinical studies across 13 different interventions in animal models of stroke, myocardial infarction, and breast cancer, we compared the ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Voelkl, Bernhard, Vogt, Lucile, Sena, Emily S., Würbel, Hanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823461/
https://www.ncbi.nlm.nih.gov/pubmed/29470495
http://dx.doi.org/10.1371/journal.pbio.2003693