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Schistosoma mansoni SmKI-1 serine protease inhibitor binds to elastase and impairs neutrophil function and inflammation

Protease inhibitors have important function during homeostasis, inflammation and tissue injury. In this study, we described the role of Schistosoma mansoni SmKI-1 serine protease inhibitor in parasite development and as a molecule capable of regulating different models of inflammatory diseases. Firs...

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Detalles Bibliográficos
Autores principales: Morais, Suellen B., Figueiredo, Barbara C., Assis, Natan R. G., Alvarenga, Debora M., de Magalhães, Mariana T. Q., Ferreira, Rafaela S., Vieira, Angélica T., Menezes, Gustavo B., Oliveira, Sergio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823468/
https://www.ncbi.nlm.nih.gov/pubmed/29425229
http://dx.doi.org/10.1371/journal.ppat.1006870