GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells

Endoplasmic reticulum (ER) membrane contact sites (MCSs) are crucial regulatory hubs in cells, playing roles in signaling, organelle dynamics, and ion and lipid homeostasis. Previous work demonstrated that the highly conserved yeast Ltc/Lam sterol transporters localize and function at ER MCSs. Our a...

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Detalles Bibliográficos
Autores principales: Besprozvannaya, Marina, Dickson, Eamonn, Li, Hao, Ginburg, Kenneth S, Bers, Donald M, Auwerx, Johan, Nunnari, Jodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823543/
https://www.ncbi.nlm.nih.gov/pubmed/29469807
http://dx.doi.org/10.7554/eLife.31019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823543/
https://www.ncbi.nlm.nih.gov/pubmed/29469807
http://dx.doi.org/10.7554/eLife.31019

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