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GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells
Endoplasmic reticulum (ER) membrane contact sites (MCSs) are crucial regulatory hubs in cells, playing roles in signaling, organelle dynamics, and ion and lipid homeostasis. Previous work demonstrated that the highly conserved yeast Ltc/Lam sterol transporters localize and function at ER MCSs. Our a...
Autores principales: | Besprozvannaya, Marina, Dickson, Eamonn, Li, Hao, Ginburg, Kenneth S, Bers, Donald M, Auwerx, Johan, Nunnari, Jodi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823543/ https://www.ncbi.nlm.nih.gov/pubmed/29469807 http://dx.doi.org/10.7554/eLife.31019 |
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