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PD-L1 expression in colorectal cancer defines three subsets of tumor immune microenvironments

OBJECTIVES: We investigated the PD-L1 expression in colorectal cancer (CRC) and in its microenvironment. RESULTS: PD-L1 was expressed in neoplastic cells (NCs) and tumor-infiltrating immune cells (IICs). All samples PD-L1+ on NCs were also on IICs. Three types of cancers could be grouped: group A(NC...

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Detalles Bibliográficos
Autores principales: Valentini, Anna Maria, Di Pinto, Federica, Cariola, Filomena, Guerra, Vito, Giannelli, Gianluigi, Caruso, Maria Lucia, Pirrelli, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823560/
https://www.ncbi.nlm.nih.gov/pubmed/29492219
http://dx.doi.org/10.18632/oncotarget.24196