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EGFR is involved in dermatofibrosarcoma protuberans progression to high grade sarcoma

Dermatofibrosarcoma protuberans (DFSP), amounting to 6% of all soft tissue sarcomas, has a slow growth rate, contrasting with a likelihood for local recurrence and a 10-20% evolution to higher-grade sarcoma, or “transformed DFSP” (DFSP-T). At molecular level, the characteristic COL1A1-PDGFB rearrang...

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Detalles Bibliográficos
Autores principales: Osio, Amélie, Xu, Shuo, El Bouchtaoui, Morad, Leboeuf, Christophe, Gapihan, Guillaume, Lemaignan, Christine, Bousquet, Guilhem, Lebbé, Céleste, Janin, Anne, Battistella, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823585/
https://www.ncbi.nlm.nih.gov/pubmed/29492209
http://dx.doi.org/10.18632/oncotarget.23899