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Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis

The PI3K/AKT/mTOR pathway is an intracellular signalling pathway that regulates cell activation. proliferation, metabolism and apoptosis. Increasing body of data suggests that alterations in the PI3K/AKT/mTOR pathway may result in an enhanced susceptibility to autoimmunity. Multiple Sclerosis (MS) i...

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Detalles Bibliográficos
Autores principales: Mammana, Santa, Bramanti, Placido, Mazzon, Emanuela, Cavalli, Eugenio, Basile, Maria Sofia, Fagone, Paolo, Petralia, Maria Cristina, McCubrey, James Andrew, Nicoletti, Ferdinando, Mangano, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823598/
https://www.ncbi.nlm.nih.gov/pubmed/29492193
http://dx.doi.org/10.18632/oncotarget.23862