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Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis

The PI3K/AKT/mTOR pathway is an intracellular signalling pathway that regulates cell activation. proliferation, metabolism and apoptosis. Increasing body of data suggests that alterations in the PI3K/AKT/mTOR pathway may result in an enhanced susceptibility to autoimmunity. Multiple Sclerosis (MS) i...

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Detalles Bibliográficos
Autores principales:	Mammana, Santa, Bramanti, Placido, Mazzon, Emanuela, Cavalli, Eugenio, Basile, Maria Sofia, Fagone, Paolo, Petralia, Maria Cristina, McCubrey, James Andrew, Nicoletti, Ferdinando, Mangano, Katia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823598/ https://www.ncbi.nlm.nih.gov/pubmed/29492193 http://dx.doi.org/10.18632/oncotarget.23862

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