New localization and function of calpain-2 in nucleoli of colorectal cancer cells in ribosomal biogenesis: effect of KRAS status

Calpain-2 belongs to a family of pleiotropic Cys-proteases with modulatory rather than degradative functions. Calpain (CAPN) overexpression has been controversially correlated with poor prognosis in several cancer types, including colorectal carcinoma (CRC). However, the mechanisms of substrate-reco...

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Detalles Bibliográficos
Autores principales: Telechea-Fernández, Marcelino, Rodríguez-Fernández, Lucia, García, Concha, Zaragozá, Rosa, Viña, Juan, Cervantes, Andrés, García-Trevijano, Elena R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823616/
https://www.ncbi.nlm.nih.gov/pubmed/29507677
http://dx.doi.org/10.18632/oncotarget.23888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823616/
https://www.ncbi.nlm.nih.gov/pubmed/29507677
http://dx.doi.org/10.18632/oncotarget.23888

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