Let-7c inhibits migration and epithelial–mesenchymal transition in head and neck squamous cell carcinoma by targeting IGF1R and HMGA2

To elucidate the molecular mechanisms underlying the progression of head and neck squamous cell carcinoma (HNSCC), we investigated the function of let-7c as a tumor suppressor. Let-7c expression was significantly down-regulated in HNSCC tumor tissues and cell lines. In vitro and in vivo studies reve...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Bo, Ishinaga, Hajime, Midorikawa, Kaoru, Nakamura, Satoshi, Hiraku, Yusuke, Oikawa, Shinji, Ma, Ning, Takeuchi, Kazuhiko, Murata, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823619/
https://www.ncbi.nlm.nih.gov/pubmed/29507664
http://dx.doi.org/10.18632/oncotarget.23826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823619/
https://www.ncbi.nlm.nih.gov/pubmed/29507664
http://dx.doi.org/10.18632/oncotarget.23826

Ejemplares similares