VEGFR2-specific FnCAR effectively redirects the cytotoxic activity of T cells and YT NK cells

T and NK cells armed with chimeric antigen receptors (CAR) are promising tools for the specific elimination of cancer cells. In most CAR designs implemented to date, the recognition of target cells is mediated by single-chain variable fragments (scFvs) derived from murine monoclonal antibodies. This...

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Detalles Bibliográficos
Autores principales: Kulemzin, Sergey V., Gorchakov, Andrey A., Chikaev, Anton N., Kuznetsova, Valeriya V., Volkova, Olga Y., Matvienko, Daria A., Petukhov, Alexey V., Zaritskey, Andrey Y., Taranin, Alexandr V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823625/
https://www.ncbi.nlm.nih.gov/pubmed/29507671
http://dx.doi.org/10.18632/oncotarget.24078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823625/
https://www.ncbi.nlm.nih.gov/pubmed/29507671
http://dx.doi.org/10.18632/oncotarget.24078

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