Development of novel miR-129 mimics with enhanced efficacy to eliminate chemoresistant colon cancer stem cells

BACKGROUND: Resistance to 5-Fluorouracil (5-FU) based chemotherapy is the major reason for failure of treating patients with advanced colorectal cancer. MATERIALS AND METHODS: In this study, we developed a novel miR-129 mimic with potent efficacy in eliminating resistant colon cancer stem cells both...

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Detalles Bibliográficos
Autores principales: Wu, Ning, Fesler, Andrew, Liu, Hua, Ju, Jingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823633/
https://www.ncbi.nlm.nih.gov/pubmed/29507661
http://dx.doi.org/10.18632/oncotarget.22322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823633/
https://www.ncbi.nlm.nih.gov/pubmed/29507661
http://dx.doi.org/10.18632/oncotarget.22322

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