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Notoginsenoside R1 ameliorates diabetic encephalopathy by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation

Numerous researches supported that oxidative stress and inflammation play important roles in the development of diabetic encephalopathy (DEP). Notoginsenoside R1 (NGR1), one major component of Panax notoginseng, is believed to have anti-oxidative, anti-inflammatory and neuroprotective properties. Ho...

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Detalles Bibliográficos
Autores principales: Zhai, Yadong, Meng, Xiangbao, Luo, Yun, Wu, Yongmei, Ye, Tianyuan, Zhou, Ping, Ding, Shilan, Wang, Min, Lu, Senbao, Zhu, Lili, Sun, Guibo, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823646/
https://www.ncbi.nlm.nih.gov/pubmed/29507694
http://dx.doi.org/10.18632/oncotarget.24295