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African swine fever virus encodes for an E2-ubiquitin conjugating enzyme that is mono- and di-ubiquitinated and required for viral replication cycle

African swine fever virus is the etiological agent of a contagious and fatal acute haemorrhagic viral disease for which there are no vaccines or therapeutic options. The ASFV encodes for a putative E2 ubiquitin conjugating enzyme (ORF I215L) that shows sequence homology with eukaryotic counterparts....

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Detalles Bibliográficos
Autores principales: Freitas, Ferdinando B., Frouco, Gonçalo, Martins, Carlos, Ferreira, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823848/
https://www.ncbi.nlm.nih.gov/pubmed/29472632
http://dx.doi.org/10.1038/s41598-018-21872-2