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African swine fever virus encodes for an E2-ubiquitin conjugating enzyme that is mono- and di-ubiquitinated and required for viral replication cycle
African swine fever virus is the etiological agent of a contagious and fatal acute haemorrhagic viral disease for which there are no vaccines or therapeutic options. The ASFV encodes for a putative E2 ubiquitin conjugating enzyme (ORF I215L) that shows sequence homology with eukaryotic counterparts....
Autores principales: | Freitas, Ferdinando B., Frouco, Gonçalo, Martins, Carlos, Ferreira, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823848/ https://www.ncbi.nlm.nih.gov/pubmed/29472632 http://dx.doi.org/10.1038/s41598-018-21872-2 |
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