Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility

Single-nucleotide variants that underlie phenotypic variation can affect chromatin occupancy of transcription factors (TFs). To delineate determinants of in vivo TF binding and chromatin accessibility, we introduce an approach that compares ChIP-seq and DNase-seq data sets from genetically divergent...

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Detalles Bibliográficos
Autores principales: Behera, Vivek, Evans, Perry, Face, Carolyne J., Hamagami, Nicole, Sankaranarayanan, Laavanya, Keller, Cheryl A., Giardine, Belinda, Tan, Kai, Hardison, Ross C., Shi, Junwei, Blobel, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823854/
https://www.ncbi.nlm.nih.gov/pubmed/29472540
http://dx.doi.org/10.1038/s41467-018-03082-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823854/
https://www.ncbi.nlm.nih.gov/pubmed/29472540
http://dx.doi.org/10.1038/s41467-018-03082-6

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