Nanogels of dual inhibitor-modified hyaluronic acid function as a potent inhibitor of amyloid β-protein aggregation and cytotoxicity

Inhibition of amyloid β-protein (Aβ) aggregation is considered as a promising strategy for the prevention and treatment of Alzheimer’s disease. Epigallocatechin-3-gallate (EGCG) and curcumin have been recognized as effective inhibitors of Aβ aggregation. Herein, we proposed dual-inhibitor modificati...

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Detalles Bibliográficos
Autores principales: Jiang, Zhiqiang, Dong, Xiaoyan, Yan, Xin, Liu, Yang, Zhang, Lin, Sun, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823891/
https://www.ncbi.nlm.nih.gov/pubmed/29472606
http://dx.doi.org/10.1038/s41598-018-21933-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823891/
https://www.ncbi.nlm.nih.gov/pubmed/29472606
http://dx.doi.org/10.1038/s41598-018-21933-6

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