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Nanogels of dual inhibitor-modified hyaluronic acid function as a potent inhibitor of amyloid β-protein aggregation and cytotoxicity
Inhibition of amyloid β-protein (Aβ) aggregation is considered as a promising strategy for the prevention and treatment of Alzheimer’s disease. Epigallocatechin-3-gallate (EGCG) and curcumin have been recognized as effective inhibitors of Aβ aggregation. Herein, we proposed dual-inhibitor modificati...
Autores principales: | Jiang, Zhiqiang, Dong, Xiaoyan, Yan, Xin, Liu, Yang, Zhang, Lin, Sun, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823891/ https://www.ncbi.nlm.nih.gov/pubmed/29472606 http://dx.doi.org/10.1038/s41598-018-21933-6 |
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