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Early sclerostin expression explains bone formation inhibition before arthritis onset in the rat adjuvant-induced arthritis model
Periarticular bone loss in rheumatoid arthritis (RA) is considered to be mainly related to synovial inflammation. However, strong bone loss has also described at the time of arthritis onset. Recently, a paradoxical exacerbation of joint damage was described when blocking sclerostin in various arthri...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823923/ https://www.ncbi.nlm.nih.gov/pubmed/29472591 http://dx.doi.org/10.1038/s41598-018-21886-w |