Early sclerostin expression explains bone formation inhibition before arthritis onset in the rat adjuvant-induced arthritis model

Periarticular bone loss in rheumatoid arthritis (RA) is considered to be mainly related to synovial inflammation. However, strong bone loss has also described at the time of arthritis onset. Recently, a paradoxical exacerbation of joint damage was described when blocking sclerostin in various arthri...

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Detalles Bibliográficos
Autores principales: Courbon, Guillaume, Lamarque, Raphaëlle, Gerbaix, Maude, Caire, Robin, Linossier, Marie-Thérèse, Laroche, Norbert, Thomas, Mireille, Thomas, Thierry, Vico, Laurence, Marotte, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823923/
https://www.ncbi.nlm.nih.gov/pubmed/29472591
http://dx.doi.org/10.1038/s41598-018-21886-w

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