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Transcription Factor Target Gene Network governs the Logical Abstraction Analysis of the Synthetic Circuit in Leishmaniasis
With the advent of synthetic biology in medicine many synthetic or engineered proteins have made their way to therapeutics and diagnostics. In this paper, the downstream gene network of CD14-TNF-EGFR pathway in leishmaniasis, a tropical disease, is reconstructed. Network analysis showed that NFkB li...
Autores principales: | Mol, Milsee, Kosey, Dipali, Boppana, Ramanamurthy, Singh, Shailza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823942/ https://www.ncbi.nlm.nih.gov/pubmed/29472639 http://dx.doi.org/10.1038/s41598-018-21840-w |
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