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Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells

Chronic obstructive pulmonary disease (COPD) is a serious global health problem characterized by chronic airway inflammation, progressive airflow limitation and destruction of lung parenchyma. Remodeling of the bronchial airways in COPD includes changes in both the bronchial epithelium and the subep...

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Detalles Bibliográficos
Autores principales: Hedström, Ulf, Hallgren, Oskar, Öberg, Lisa, DeMicco, Amy, Vaarala, Outi, Westergren-Thorsson, Gunilla, Zhou, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823945/
https://www.ncbi.nlm.nih.gov/pubmed/29472603
http://dx.doi.org/10.1038/s41598-018-21727-w