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Generation of Isthmic Organizer-Like Cells from Human Embryonic Stem Cells

The objective of this study was to induce the production of isthmic organizer (IsO)-like cells capable of secreting fibroblast growth factor (FGF) 8 and WNT1 from human embryonic stem cells (ESCs). The precise modulation of canonical Wnt signaling was achieved in the presence of the small molecule C...

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Detalles Bibliográficos
Autores principales: Lee, Junwon, Choi, Sang-Hwi, Lee, Dongjin R, Kim, Dae-Sung, Kim, Dong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824020/
https://www.ncbi.nlm.nih.gov/pubmed/29385674
http://dx.doi.org/10.14348/molcells.2018.2210