Cargando…

The Role of Hippo Pathway in Cancer Stem Cell Biology

The biological significance and deregulation of the Hippo pathway during organ growth and tumorigenesis have received a surge of interest in the past decade. The Hippo pathway core kinases, MST1/2 and LATS1/2, are tumor suppressors that inhibit the oncogenic nuclear function of YAP/TAZ and TEAD. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Jae Hyung, Shin, Ji Eun, Park, Hyun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824027/
https://www.ncbi.nlm.nih.gov/pubmed/29429151
http://dx.doi.org/10.14348/molcells.2018.2242