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MiR-199a/b-5p Inhibits Lymphangiogenesis by Targeting Discoidin Domain Receptor 1 in Corneal Injury

Discoidin domain receptor 1 (DDR1) is involved in tumorigenesis and angiogenesis. However, its role in lymphangiogenesis has been unknown. Here, we tested whether downregulation of DDR1 expression by miR-199a/b can suppress lymphangiogenesis. We also aimed to identify miRNA target site(s) in the 3′...

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Detalles Bibliográficos
Autores principales: Oh, Sooeun, Seo, Minkoo, Choi, Jun-Sub, Joo, Choun-Ki, Lee, Suk Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824028/
https://www.ncbi.nlm.nih.gov/pubmed/29429150
http://dx.doi.org/10.14348/molcells.2018.2163