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Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status

A comprehensive search in literature and published US Food and Drug Administration reviews was conducted to assess whether physiologically based pharmacokinetic (PBPK) modeling could be prospectively used to predict clinical food effect on oral drug absorption. Among the 48 resulted food effect pred...

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Detalles Bibliográficos
Autores principales: Li, Mengyao, Zhao, Ping, Pan, Yuzhuo, Wagner, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824104/
https://www.ncbi.nlm.nih.gov/pubmed/29168611
http://dx.doi.org/10.1002/psp4.12260