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Leveraging Population‐Based Clinical Quantitative Phenotyping for Drug Repositioning

Computational drug repositioning methods can scalably nominate approved drugs for new diseases, with reduced risk of unforeseen side effects. The majority of methods eschew individual‐level phenotypes despite the promise of biomarker‐driven repositioning. In this study, we propose a framework for di...

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Detalles Bibliográficos
Autores principales: Brown, Adam S., Rasooly, Danielle, Patel, Chirag J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824113/
https://www.ncbi.nlm.nih.gov/pubmed/28941007
http://dx.doi.org/10.1002/psp4.12258