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Leveraging Population‐Based Clinical Quantitative Phenotyping for Drug Repositioning
Computational drug repositioning methods can scalably nominate approved drugs for new diseases, with reduced risk of unforeseen side effects. The majority of methods eschew individual‐level phenotypes despite the promise of biomarker‐driven repositioning. In this study, we propose a framework for di...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824113/ https://www.ncbi.nlm.nih.gov/pubmed/28941007 http://dx.doi.org/10.1002/psp4.12258 |