Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations

The unmet medical need of providing evidence‐based pharmacotherapy for pregnant women is recognized by the regulatory bodies. Physiologically based pharmacokinetic (PBPK) modeling offers an attractive platform to quantify anticipated changes in the pharmacokinetics (PKs) of drugs during pregnancy. R...

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Detalles Bibliográficos
Autores principales: Ke, Alice Ban, Greupink, Rick, Abduljalil, Khaled
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824116/
https://www.ncbi.nlm.nih.gov/pubmed/29349870
http://dx.doi.org/10.1002/psp4.12274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824116/
https://www.ncbi.nlm.nih.gov/pubmed/29349870
http://dx.doi.org/10.1002/psp4.12274

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