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Frequency‐Domain Response Analysis for Quantitative Systems Pharmacology Models

Drug dosing regimen can significantly impact drug effect and, thus, the success of treatments. Nevertheless, trial and error is still the most commonly used method by conventional pharmacometric approaches to optimize dosing regimen. In this tutorial, we utilize four distinct classes of quantitative...

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Detalles Bibliográficos
Autores principales: Schulthess, Pascal, Post, Teun M., Yates, James, van der Graaf, Piet H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824121/
https://www.ncbi.nlm.nih.gov/pubmed/29193852
http://dx.doi.org/10.1002/psp4.12266