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Genetic bypass of essential RNA repair enzymes in budding yeast

RNA repair enzymes catalyze rejoining of an RNA molecule after cleavage of phosphodiester linkages. RNA repair in budding yeast is catalyzed by two separate enzymes that process tRNA exons during their splicing and HAC1 mRNA exons during activation of the unfolded protein response (UPR). The RNA lig...

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Detalles Bibliográficos
Autores principales: Cherry, Patrick D., White, Laura K., York, Kerri, Hesselberth, Jay R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824351/
https://www.ncbi.nlm.nih.gov/pubmed/29212664
http://dx.doi.org/10.1261/rna.061788.117