Purine– and pyrimidine–triple-helix-forming oligonucleotides recognize qualitatively different target sites at the ribosomal DNA locus

Triplexes are noncanonical DNA structures, which are functionally associated with regulation of gene expression through ncRNA targeting to chromatin. Based on the rules of Hoogsteen base-pairing, polypurine sequences of a duplex can potentially form triplex structures with single-stranded oligonucle...

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Detalles Bibliográficos
Autores principales: Maldonado, Rodrigo, Filarsky, Michael, Grummt, Ingrid, Längst, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824356/
https://www.ncbi.nlm.nih.gov/pubmed/29222118
http://dx.doi.org/10.1261/rna.063800.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824356/
https://www.ncbi.nlm.nih.gov/pubmed/29222118
http://dx.doi.org/10.1261/rna.063800.117

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