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Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4–NOT complex to elicit repression of mRNA targets

Drosophila melanogaster Bag-of-marbles (Bam) promotes germline stem cell (GSC) differentiation by repressing the expression of mRNAs encoding stem cell maintenance factors. Bam interacts with Benign gonial cell neoplasm (Bgcn) and the CCR4 deadenylase, a catalytic subunit of the CCR4–NOT complex. Ba...

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Detalles Bibliográficos
Autores principales: Sgromo, Annamaria, Raisch, Tobias, Backhaus, Charlotte, Keskeny, Csilla, Alva, Vikram, Weichenrieder, Oliver, Izaurralde, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824357/
https://www.ncbi.nlm.nih.gov/pubmed/29255063
http://dx.doi.org/10.1261/rna.064584.117