Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA

Microorganisms have universally adapted their RNAs and proteins to survive at a broad range of temperatures and growth conditions. However, for RNAs, there is little quantitative understanding of the effects of mutations on function at high temperatures. To understand how variant tRNA function is af...

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Detalles Bibliográficos
Autores principales: Payea, Matthew J., Sloma, Michael F., Kon, Yoshiko, Young, David L., Guy, Michael P., Zhang, Xiaoju, De Zoysa, Thareendra, Fields, Stanley, Mathews, David H., Phizicky, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824359/
https://www.ncbi.nlm.nih.gov/pubmed/29259051
http://dx.doi.org/10.1261/rna.064642.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824359/
https://www.ncbi.nlm.nih.gov/pubmed/29259051
http://dx.doi.org/10.1261/rna.064642.117

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