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Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA
Microorganisms have universally adapted their RNAs and proteins to survive at a broad range of temperatures and growth conditions. However, for RNAs, there is little quantitative understanding of the effects of mutations on function at high temperatures. To understand how variant tRNA function is af...
Autores principales: | Payea, Matthew J., Sloma, Michael F., Kon, Yoshiko, Young, David L., Guy, Michael P., Zhang, Xiaoju, De Zoysa, Thareendra, Fields, Stanley, Mathews, David H., Phizicky, Eric M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824359/ https://www.ncbi.nlm.nih.gov/pubmed/29259051 http://dx.doi.org/10.1261/rna.064642.117 |
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